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Onco Checklist >> CLL Staging


DiagnosisResult
Peripheral blood smears
Immunophenotyping
p53-mutation
IgVH-mutation status
FISH
Bone marrow biopsy (only in selected cases)


Patient historyResult
Weight loss (>10% in 6 months)
Night sweats (with changing of clothes)
Fever (>38C) with no other cause
Itching
Lymphocyte doubling time


Physical examinationResult
Lymph nodes, heart-/lung, abdominal examination, edemas? Skin changes?
Size of spleen / liver (palpable below ribs?)
Height and weight
Blood pressure and frequency



Clinical chemistryResult
Blood count
Electrolytes
Creatinine
Creatinine clearance (calculated)
Liver enzymes (AST; ALT; G-GT)
Bilirubine
ESR
AP
Coagulation parameters (incl. ATIII, D-dimers, fibrinogen)
LDH
CRP
Elektrophoresis, IgG, IgA, IgM (deficiency?)
Beta-2-mikroglobuline
Tyrosine kinase


VirologyResult
HIV 1 and 2
Hepatitis B
Hepatitis C
EBV (?)



Imaging and other examintationsResult
Chest X-ray
Sonography of abdomen
CT of thorax and abdomen (if necessary for staging of lymph adenopathy)
Echocardiography
Spirometry
EKG


StudiesResult
Inclusion in study possible?yes no
Study:



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