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Onco Checklist >> Multiple Myeloma Staging


HistologyResult
Bone marrow aspiration and biopsy, peripheral blood smears
Cytogenetics / molecular biology, if necessary to estimate prognosis


Patient history
Result
Weight loss (>10% in 6 months)
Night sweats (requiring change of clothes)
Fever (>38C) without any other cause


Physical examinationResult
Lymph nodes, heart-/lung, abdominal examination, edema? Skin lesions?
Height and weight
Blood pressure and pulse



Clinical chemistry Result
Proteins:
SERUM - Immunoglobulins quantitative (IgG, IgA, IgM), serum electropheresis, immune fixation, light chains, beta-2-microglobulin, albumin, total protein
24h-URINE - (total-)protein excretion, creatinine clearance, light chains, immune fixation
Electrolytes
Creatinine
Creatinine clearance (calculated)
Liver enzymes (AST; ALT; G-GT)
Bilirubin
ESR
Alk Phos
Coagulation parameters (incl. ATIII, D-dimers, fibrinogen)
LDH
CRP


VirologyResult
HIV 1 and 2
Hepatitis B
Hepatitis C



Imaging and further diagnosticsResult
Whole body X-ray "plasmacytoma" or whole body MRI
Chest X-ray
Sonography of abdomen
Echocardiography
Spirometry
EKG


StudiesResult
Study inclusion possible?
yes no
Study:



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